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Before you take any serotonin supplement, it’s important to understand a little bit about them and especially how they work together.

Tryptophan more readily enters the brain, but 5-HTP requires one less step to convert into serotonin.

Serotonin supplements like specific amino acids, vitamins, minerals and herbs increase serotonin levels helping depression and other brain-related disorders.

Serotonin is a neurotransmitter that plays a large role in mood, learning, appetite control, and sleep.

Vitamin B6 (pyridoxine): Vitamin B6 must be present to facilitate conversion of either 5-HTP or tryptophan into serotonin (17, 18).

Often 5-HTP or tryptophan supplements also contain B6 for this reason.